The Week 18 NFL schedule features a matchup between AFC South teams that have been eliminated from postseason contention when the Indianapolis Colts host the Jacksonville Jaguars on Sunday. The Colts are 7-9 overall and 4-3 at home, while the Jags are 4-12 overall and 1-7 on the road. Jacksonville is looking to build off its 20-13 win over the Tennessee Titans in Week 17, while Indianapolis is looking to bounce back from its 45-33 upset loss to the New York Giants. Both teams are 9-7 against the spread this season. Quarterback Anthony Richardson (back) is out for the Colts.
Kickoff is set for 1 p.m. ET on Sunday at Lucas Oil Stadium. The Colts are favored by 3.5 points in the latest Colts vs. Jaguars odds, while the over/under is 43.5 points, per SportsLine consensus. Before entering any Jaguars vs. Colts picks, you’ll want to see the NFL predictions and betting advice from the proven computer simulation model at SportsLine.
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 18 of the 2024 NFL season on a 30-14 betting hot streak on top-rated NFL picks this year, a stunning 68% success rate. Longer term, it is on a 210-142 roll on top-rated NFL picks that dates back to the 2017 season and a 64-35 roll on top-rated NFL picks since Week 7 of 2022.
The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone following at sportsbooks and on betting apps has seen strong returns.
The model has set its sights on Jaguars vs. Colts and just locked in its Week 18 NFL picks and predictions. You can head to SportsLine now to see the model’s picks. Here are several NFL betting lines for the game:
- Colts vs. Jaguars spread: Colts -3.5
- Colts vs. Jaguars over/under: 43.5 points
- Colts vs. Jaguars money line: Colts -196, Jaguars +162
- Colts vs. Jaguars picks: See picks at SportsLine
- Colts vs. Jaguars streaming: FuboTV (Try for free)
Why the Colts can cover
The Colts are coming off arguably their worst loss of the season in Week 17. Despite entering the game favored by more than a touchdown, Indianapolis lost to the lowly New York Giants 45-33, ending their hopes for qualifying for the postseason. The Colts will once again turn to veteran quarterback Joe Flacco in this game. In seven appearances (five starts) this season, Flacco has thrown for 1,497 yards, 11 touchdowns, and seven interceptions.
Running back Jonathan Taylor has been on a tear for the Colts over the last month. The 2021 NFL rushing champion has 546 yards and five touchdowns in his last four games. In 13 games this season, Taylor has 1,254 rushing yards and 10 rushing touchdowns on 269 carries. He’s also caught 17 passed for 133 yards and a score. See which team to pick here.
Why the Jaguars can cover
The Jaguars are coming off a win and one of their best performances of the season in their 20-13 Week 17 win over the Titans. Mac Jones, who has filled in for Trevor Lawrence (shoulder) since Dec. 1, threw for 174 yards and two touchdowns. The Jacksonville defense was stellar in the win, limiting Tennessee to 337 total yards and 13 points.
The Jaguars have one of the most explosive wide receivers in the NFL to build around in Brian Thomas Jr.. The 6-foot-3 rookie out of LSU was the No. 23 pick in the 2024 NFL Draft, and he has already established himself as the team’s No. 1 wide receiver. Thomas enters Week 18 with 80 catches for 1,179 yards and 10 touchdowns on 122 targets. See which team to pick here.
How to make Jaguars vs. Colts picks
The model has simulated Colts vs. Jaguars 10,000 times and the results are in. The model is leaning Over on the point total, projecting 53 combined points, and it’s also generated a point-spread pick that is hits in 60% of computer simulations. You can only see the model’s pick at SportsLine.
So who wins Colts vs. Jaguars on Sunday, and which side of the spread hits in 60% of simulations? Visit SportsLine right now to see which side of the Jaguars vs. Colts spread you should be all over, all from the model on a 210-142 roll on its top-rated NFL picks, and find out.