The Detroit Lions (13-2) will visit the San Francisco 49ers (6-9) in an NFC showdown on Monday Night Football to conclude the Week 17 NFL schedule. The Lions are fighting to lock down the No. 1 seed in the NFC playoff bracket. In Week 16, the Lions blew out the Chicago Bears, 34-17. The Niners are looking to play spoiler since they have been eliminated from playoff contention. Last week, the 49ers fell to the Miami Dolphins, 29-17. The latest Lions vs. 49ers forecast is calling for partly cloudy skies, light winds, and temperatures around 50.
Kickoff from Levi’s Stadium in San Francisco is set for 8:15 p.m. ET. Detroit is a 3.5-point favorite in the latest Lions vs. 49ers odds from the SportsLine Consensus, while the over/under for total points scored is 50. The Lions are -216 money-line favorites (risk $216to win $100), while the 49ers are +179 underdogs. Before locking in any Lions vs. 49ers picks, make sure to check out the NFL predictions and betting advice from the SportsLine Projection Model.
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 17 of the 2024 NFL season on a 28-12 betting hot streak on top-rated NFL picks this year, a stunning 70% success rate. Longer term, it is on a 208-140 roll on top-rated NFL picks that dates back to the 2017 season and a 62-33 roll on top-rated NFL picks since Week 7 of 2022.
The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone following at sportsbooks and on betting apps has seen strong returns.
Now, the model has simulated Lions vs. 49ers 10,000 times and just revealed its coveted NFL picks and NFL betting predictions. You can head to SportsLine now to see the model’s picks. Here are several NFL odds and NFL betting lines for Lions vs. 49ers:
- Lions vs. 49ers spread: Detroit -3.5
- Lions vs. 49ers over/under: 50 points
- Lions vs. 49ers money line: Detroit -216, San Francisco +179
- DET: Lions are 10-5 against the spread this season
- SF: 49ers are 5-10 against the spread this season
- Lions vs. 49ers picks: See picks at SportsLine
- Lions vs. 49ers streaming: FuboTV (Try for free)
Why the Lions can cover
Detroit’s offense is ranked second in total yardage (408.6) and passing yardage (264.7). Quarterback Jared Goff is the engineer of this potent unit. Goff is second in passing yards (4,095), fourth in passing touchdowns (33) and eighth in QBR (66.3). The Cal product has thrown for multiple passing touchdowns in four straight games. Last week versus the Bears, Goff went 23-of-32 for 336 yards and three passing touchdowns.
Running back Jahmyr Gibbs is a dynamic playmaker who can handle the load with David Montgomery (knee) out. The Alabama product is seventh in rushing yards (1,156) and rushing touchdowns (12). In addition, he has added 440 receiving yards. See who to back at SportsLine.
Why the 49ers can cover
Quarterback Brock Purdy has completed 65% of his throws for 3,487 yards and 17 passing touchdowns this season. Purdy has four games with 300-plus yards, including two in the last three games. In the loss to the Dolphins, the 24-year-old had 313 passing yards and two passing scores.
Tight end George Kittle is a physical blocker and reliable pass-catcher. He leads the team in receptions (68), receiving yards (967), and touchdowns (8). The Iowa product has 18 receptions of 20-plus yards in 2024. The 31-year-old has gone over 100 receiving yards in two of his last three games. In Week 14 over the Bears, Kittle had six catches for a season-high 151 receiving yards. See who to back at SportsLine.
How to make Lions vs. 49ers picks
The model is leaning Over the total, projecting 51 combined points. It also says one side of the spread cashes in over 50% of simulations. You can head to SportsLine to see the model’s picks.
So who wins 49ers vs. Lions on Monday Night Football, and which side of the spread hits over 50% of the time? Visit SportsLine now to see which side of the 49ers vs. Lions spread to back, all from the model that has returned well over $7,000 on top-rated NFL picks.
