C.J. Stroud and Anthony Richardson will square off in Week 1 of the NFL schedule as the Colts host the Texans. Houston is a 2.5-point favorite in the latest Week 1 NFL odds in a game that features two teams with identical spread records in 2023. Both squads went 9-8 against the number last year, making this the only game on the Week 1 NFL schedule in which the teams had the same spread record a year ago. Furthermore, they split their two matchups last year, with each team covering on the road.
If recent NFL spreads are how you make your Week 1 NFL picks, then you’ll have to rely on another stat else for this matchup. Fortunately, there are plenty of decisive NFL betting trends that could make your NFL betting strategy for this game much clearer. Before you make any Week 1 NFL picks, you need to see the NFL against the spread, over-under, and money line predictions powered by SportsLine AI.
Built using cutting-edge artificial intelligence and machine learning techniques by SportsLine’s Data Science team, AI Predictions and AI Ratings are generated for each game. The AI predictions are determined by statistically learning from each team’s historical data and then quantitatively evaluating the strength of the opponent’s defense by assigning a numeric value out of 100 called a matchup score.
Once a prediction is formulated, the AI rating is generated using the prediction, the matchup score, and the odds of the market. For example, you could see an A-rating on an over bet if a team is facing a poor defense, their prediction differs from the line and there are favorable odds.
In addition, SportsLine AI is the first fully automated predictive model at SportsLine. It continuously refreshes on the most recent available data and can help you spot the biggest discrepancies in the lines. Last season, SportsLine’s AI PickBot hit a whopping 1,674 4.5- and 5-star prop picks. Anyone who has followed it is way up.
For Week 1, the AI PickBot has evaluated the NFL odds and provided NFL predictions for all 16 games. You can only see the AI predictions for the Week 1 NFL schedule here.
Top Week 1 NFL AI picks
After analyzing every game in Week 1, the AI PickBot says the Broncos cover as 5.5-point underdogs against the Seahawks in a game that has earned an A-rated pick. The Russell Wilson trade between these teams netted Seattle lots of draft picks that they’ve used on defensive players. However, many of those players haven’t progressed as expected as Seattle was among the league’s worst defensive teams last season. It ranked among the bottom three in total defense, rushing yards allowed and third-down defense, while no team gave up more first downs than the Seahawks.
A porous defense is just what rookie Bo Nix wants to see in his first start. His accuracy is elite, as he finished among the top two in completion percentage in each of his years at Oregon, and he has a master playcaller in Sean Payton. Speaking of Payton, he won’t be fazed by the frenzied environment that Lumen Field has as he’s won his last two games as a coach in Seattle and has beaten the Seahawks three straight times overall. Add in that Seattle failed to cover in all five of its games versus AFC teams last year, and the AI PickBot is strongly backing Denver at +5.5. See its other Week 1 football predictions and football picks at SportsLine.
How to make Week 1 NFL picks
In addition, the AI PickBot has generated eight more A-rated picks for Week 1. You need to see the AI PickBot’s analysis before making any Week 1 NFL bets. You can only see it at SportsLine.
Who wins and covers each Week 1 NFL game, and which A-rated picks should you be targeting? Visit SportsLine now to see the top NFL picks against the spread, over-under, and on money line, all from the brand-new SportsLine AI PickBot that nailed 1,674 top-rated picks last season.
